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Success Story

Awards - First Round

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Summary

180 proposals were submitted, of which 170 were peer reviewed (10 were returned without review). 12 projects were awarded, for a total of $14.6M. Cost share provided by the applicants was $13.4M. Additional leverage is provided by current and pending Federal awards, though this is not included in our estimate of "immediate" cost share. Longer-term, it is expected that Fund awardees will provide large-scale leverage via Federal and private sector support of follow-on activities and commercialization.

These awards support development of new technologies or extend existing technologies, create essential new technical infrastructure in Indiana, and enable the establishment of centers of excellence in technologies critical to the growth of Indiana's high technology sector.

Of the 12 first-round awards, 8 have major biomedical objectives, including: validation of the therapeutic use of devices, tissue engineering, development of new orthopedic approaches and materials, dental imaging, and applications of mid-IR sensing. Two biomedical awards provide essential infrastructure to the medical sciences in Indiana: the rodent resource and the medical genomics center. Such infrastructure provides an important competitive advantage to Indiana researchers in attracting Federal research and development funds.

A major high technology cluster in orthopedic implants exists in the State. This group of companies has an important need to develop new materials and technologies in order to assure its long-term viability. Two awards (#20, Schmid; and #32, Varma) broaden the ties between the orthopedic cluster and the academic research base in the State. In addition, the rapidly evolving tissue- engineering field is strongly supported by the award to Hiles (#86).

Future progress in the understanding of disease processes, and the biological response to therapeutics, will be utterly dependent on the ability to characterize global changes in genome expression (and the correlation of those changes with phenotype) and on the ability to create, maintain, and characterize genetically modified rodents. The awards to Edenberg (#112) and to Li (#109) provide this critical infrastructure to the Indiana biomedical research community.

Diagnostic and therapeutic device development supports another important cluster within the State (awards to Gore, #96; Stookey, #111; and Kraemer, #122), although the objectives of the Gore project extend well beyond biomedical applications.

The sole information technologies award made in the first round targets medical multimedia database management (Elmagarmid, #71), which is an area of growing importance as the health care community moves to more efficient integration of all aspects of health information management. Similarly, application of advanced computational techniques to the development of the next generation of jet engines is supported by the award to Anand (#158). Advances in separation science, which are likely to have major impact on chemical, pharmaceutical, and food industries are supported by the award to Wang (#28).

The award to Baxter (#155), which involves a collaboration between IU Bloomington and the University of Notre Dame, aims to develop Hoosier expertise in spintronics research-an area of major potential commercial optoelectronics development.